Inter-alpha-trypsin inhibitor promotes bronchial epithelial repair after injury through vitronectin binding.


Pulmonary epithelial injury is central to the pathogenesis of many lung diseases, such as asthma, pulmonary fibrosis, and the acute respiratory distress syndrome. Regulated epithelial repair is crucial for lung homeostasis and prevents scar formation and inflammation that accompany dysregulated healing. The extracellular matrix (ECM) plays an important role… (More)
DOI: 10.1074/jbc.M808560200


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