Inter-Laboratory Robustness of Next- Generation Bile Acid Study in Mice and Humans: International Ring Trial Involving 12 Laboratories

@inproceedings{Pham2016InterLaboratoryRO,
  title={Inter-Laboratory Robustness of Next- Generation Bile Acid Study in Mice and Humans: International Ring Trial Involving 12 Laboratories},
  author={Hai The Pham and Kathrin Arnhard and Yasmin F. Asad and Lu Deng and Thomas K Felder and Lisa St. John-Williams and Volkhard W. Kaever and Michael Leadley and Nico Mitro and St{\'e}phane Muccio and Cornelia Prehn and Manfred Rauh and Ulrike Dr Rolle-Kampczyk and J. Will Thompson and Olaf Uhl and Maria Malgorzata Ulaszewska and Michael Vogeser and David S. Wishart and Therese Koal},
  year={2016}
}
Background: The increasing relevance of individual bile acids quantification in biological samples requires analytical standardization to guarantee robustness and reliability of laboratory results. We have organized the first international ring trial, carried out in 12 laboratories, to evaluate the newly developed LC-MS/MS–based test kit for bile acid analysis. Methods: Each laboratory received a Biocrates ® Bile Acids Kit including system suitability test (SST) protocol. The kit is designed to… CONTINUE READING

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