Intensive resistance exercise induces lymphocyte apoptosis via cortisol and glucocorticoid receptor-dependent pathways.

@article{Krger2011IntensiveRE,
  title={Intensive resistance exercise induces lymphocyte apoptosis via cortisol and glucocorticoid receptor-dependent pathways.},
  author={Karsten Kr{\"u}ger and S Agnischock and Anja Lechtermann and Swasti Tiwari and Miti Mishra and Christian Pilat and Andrea Wagner and C Tweddell and I Gramlich and Frank Christoph Mooren},
  journal={Journal of applied physiology},
  year={2011},
  volume={110 5},
  pages={1226-32}
}
Intensive endurance exercise is known to induce lymphocyte apoptosis, which might affect immune function. Less is known about the effects of resistance exercise on apoptosis and its underlying mechanisms. In this study, subjects performed an intensive resistance test (IRT) and a moderate resistance test, and lymphocyte apoptosis, apoptosis-related parameters, and underlying mechanisms were investigated. IRT induced a significant increase of lymphocyte apoptosis 3 h after exercise, which was… CONTINUE READING

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