Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European LeukemiaNet classification.

@article{Wetzler2014IntensiveII,
  title={Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European LeukemiaNet classification.},
  author={Meir Wetzler and Krzysztof Mr{\'o}zek and Jessica Kohlschmidt and Herv{\'e} Dombret and Hartmut D{\"o}hner and Sylvain Pilorge and Utz Krug and Andrew J. Carroll and Richard A Larson and Guido Marcucci and Wolfgang Hiddemann and Thomas B{\"u}chner and Clara D. Bloomfield},
  journal={Haematologica},
  year={2014},
  volume={99 2},
  pages={308-13}
}
We investigated whether octogenarian patients with acute myeloid leukemia enrolled onto Cooperative Group clinical trials and treated with intensive induction therapy could be cured, and whether karyotype and selected molecular markers had any prognostic significance in these patients. Among 138 patients with cytogenetic information, normal karyotype was… CONTINUE READING