Intensive immunosuppression and autologous stem cell transplantation for patients with severe rheumatoid arthritis: the Leiden experience.

@article{Laar2001IntensiveIA,
  title={Intensive immunosuppression and autologous stem cell transplantation for patients with severe rheumatoid arthritis: the Leiden experience.},
  author={Jacob M van Laar and R obert J Verburg and Willem E. Fibbe and Ferdinand C. Breedveld},
  journal={The Journal of rheumatology. Supplement},
  year={2001},
  volume={64},
  pages={25-7}
}
Ten patients with active, destructive rheumatoid arthritis refractory to antirheumatic therapy enrolled in a study to evaluate the effects of intensive immunosuppression followed by autologous stem cell transplantation. Intensive immunosuppression was achieved with high dose cyclophosphamide as part of the mobilization (4 g/m2) and conditioning (200 mg/kg… CONTINUE READING