Intensive blood pressure lowering in patients with acute intracerebral haemorrhage: clinical outcomes and haemorrhage expansion. Systematic review and meta-analysis of randomised trials

@article{Boulouis2017IntensiveBP,
  title={Intensive blood pressure lowering in patients with acute intracerebral haemorrhage: clinical outcomes and haemorrhage expansion. Systematic review and meta-analysis of randomised trials},
  author={G. Boulouis and A. Morotti and J. Goldstein and A. Charidimou},
  journal={Journal of Neurology, Neurosurgery, and Psychiatry},
  year={2017},
  volume={88},
  pages={339 - 345}
}
  • G. Boulouis, A. Morotti, +1 author A. Charidimou
  • Published 2017
  • Medicine
  • Journal of Neurology, Neurosurgery, and Psychiatry
  • Introduction It is unclear whether intensive lowering of blood pressure (BP) at the acute phase of intracerebral haemorrhage (ICH) is beneficial. We performed a meta-analysis of randomised controlled trials (RCTs) to assess whether intensive BP lowering in patients with acute ICH is safe and effective in improving clinical outcomes. Methods We searched PubMed, EMBASE and the Cochrane databases for relevant RCTs and calculated pooled OR for 3-month mortality (safety outcome) and 3-month death or… CONTINUE READING

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    This study evaluates safety and efficacy of analgesia-first minimal sedation as an early antihypertensive treatment for spontaneous intracerebral hemorrhage. The analgesia-first… Expand
    ConditionsBlood Pressure Variability, Duration of ICU Treatment and Mechanical Ventilation, Early Systolic Blood Pressure Control Rate, (+2 more)
    InterventionCombination Product
    The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
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