Intensity-modulated radiotherapy (IMRT) and conventional three-dimensional conformal radiotherapy for high-grade gliomas: does IMRT increase the integral dose to normal brain?

@article{Hermanto2007IntensitymodulatedR,
  title={Intensity-modulated radiotherapy (IMRT) and conventional three-dimensional conformal radiotherapy for high-grade gliomas: does IMRT increase the integral dose to normal brain?},
  author={Ulrich Hermanto and Erik K Frija and Mingfwu J Lii and Eric L. Chang and A. O. Mahajan and Shiao Y. Woo},
  journal={International journal of radiation oncology, biology, physics},
  year={2007},
  volume={67 4},
  pages={1135-44}
}
PURPOSE To determine whether intensity-modulated radiotherapy (IMRT) treatment increases the total integral dose of nontarget tissue relative to the conventional three-dimensional conformal radiotherapy (3D-CRT) technique for high-grade gliomas. METHODS AND MATERIALS Twenty patients treated with 3D-CRT for glioblastoma multiforme were selected for a comparative dosimetric evaluation with IMRT. Original target volumes, organs at risk (OAR), and dose-volume constraints were used for replanning… CONTINUE READING