Intensity-modulated parametric mapping for simultaneous display of rapid dynamic and high-spatial-resolution breast MR imaging data.

@article{Agoston2001IntensitymodulatedPM,
  title={Intensity-modulated parametric mapping for simultaneous display of rapid dynamic and high-spatial-resolution breast MR imaging data.},
  author={Agoston T. Agoston and Bruce L. Daniel and Robert J. Herfkens and Debra M. Ikeda and Robyn L. Birdwell and S G Heiss and Anne M. Sawyer-Glover},
  journal={Radiographics : a review publication of the Radiological Society of North America, Inc},
  year={2001},
  volume={21 1},
  pages={
          217-26
        }
}
Contrast material-enhanced magnetic resonance (MR) imaging of the breast has variable specificity for differentiation of breast cancer from other enhancing conditions. Two principal strategies to improve its specificity are rapid dynamic MR imaging and high-spatial-resolution MR imaging. A method was developed of combining contemporaneously acquired dynamic and high-spatial-resolution MR imaging data into a single integrated display. Whole-breast rapid dynamic data were condensed into a color… 
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52 Citations
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13
Methods Citations
6

52 Citations

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Citation Type

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Investigation of the trade-off between temporal and spatial resolution in dynamic contrast material-enhanced bilateral magnetic resonance (MR) imaging of the breast found increased spatial resolution significantly improves diagnostic confidence and accuracy at dynamic MR imaging, even if this improvement occurs at the expense of temporal resolution.
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Properly selected thresholds in parametric imaging may be helpful in the differentiation of enhancing tissue and significantly speeds up the analysis and makes it safer as a lower rate of ROI-measurements is needed to find the strongest enhancement.
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This protocol at the charge of slightly enlarged time for measurement offers an elegant way to improve analysis of architectural features in MRM.
Color-Coded Automated Signal Intensity Curves for Detection and Characterization of Breast Lesions: Preliminary Evaluation of a New Software Package for Integrated Magnetic Resonance-Based Breast Imaging
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The novel color-coded signal intensity curve software allows lesions to be visualized as false color maps that correspond to conventional signal intensity time curves and detection and characterization of breast lesions with this method is quick and easily interpretable.
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TLDR
Quantitative parametric analysis of contrast kinetics in lesions can replace the subjective manual region of interest (ROI) method and makes a step toward standardization of MR mammography.
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TLDR
Initial experiences indicate that contrast-enhanced MR imaging at 3.0 T is nearing readiness for clinical use and differential diagnosis of enhancing lesions was possible with higher diagnostic confidence.
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TLDR
Results suggest that heterogeneity of breast lesion kinetics, as quantified by texture analysis, may contribute to computer assisted tissue characterization in DCE-MRI.
The lactating breast: contrast-enhanced MR imaging of normal tissue and cancer.
TLDR
Normal lactating glands have increased density, high T2-weighted signal intensity, and rapid moderate contrast enhancement, and breast cancers are visible during lactation owing to their lower signal intensity and more intense initial contrast enhancement with early washout compared with normal breast tissue.
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