Intensified exercise training does not alter AMPK signaling in human skeletal muscle.

@article{Clark2004IntensifiedET,
  title={Intensified exercise training does not alter AMPK signaling in human skeletal muscle.},
  author={Sally A. Clark and Z G Chen and Keegan T Murphy and Robert J. Aughey and Michael J McKenna and Bruce E. Kemp and John A. Hawley},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2004},
  volume={286 5},
  pages={E737-43}
}
The AMP-activated protein kinase (AMPK) cascade has been linked to many of the acute effects of exercise on skeletal muscle substrate metabolism, as well as to some of the chronic training-induced adaptations. We determined the effect of 3 wk of intensified training (HIT; 7 sessions of 8 x 5 min at 85% Vo2 peak) in skeletal muscle from well-trained athletes on AMPK responsiveness to exercise. Rates of whole body substrate oxidation were determined during a 90-min steady-state ride (SS) pre- and… CONTINUE READING