Intellectual development before and after the onset of infantile spasms: a controlled prospective longitudinal study in tuberous sclerosis.

@article{Humphrey2014IntellectualDB,
  title={Intellectual development before and after the onset of infantile spasms: a controlled prospective longitudinal study in tuberous sclerosis.},
  author={Ayla Humphrey and Cathy Maclean and George Basil Ploubidis and Yael E Granader and Michelle Clifford and Maisy Haslop and Brian G. R. Neville and John R. Yates and Patrick F. Bolton},
  journal={Epilepsia},
  year={2014},
  volume={55 1},
  pages={108-16}
}
OBJECTIVE Infantile spasms (IS) have long been suspected to be a risk factor for impairment in intellectual development, but there are no controlled, prospective longitudinal data in well-characterized conditions to confirm this suspicion. We tested the hypothesis in a longitudinal study of children with tuberous sclerosis (TS), who have a high risk of… CONTINUE READING