Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models.

@article{Jiang2004IntegumentPF,
  title={Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models.},
  author={T X Jiang and Randall B Widelitz and Wei-Min Shen and Peter Will and D Wu and Chih-Min Lin and H S Jung and Cheng-Ming Chuong},
  journal={The International journal of developmental biology},
  year={2004},
  volume={48 2-3},
  pages={117-35}
}
Pattern formation is a fundamental morphogenetic process. Models based on genetic and epigenetic control have been proposed but remain controversial. Here we use feather morphogenesis for further evaluation. Adhesion molecules and/or signaling molecules were first expressed homogenously in feather tracts (restrictive mode, appear earlier) or directly in bud or inter-bud regions ( de novo mode, appear later). They either activate or inhibit bud formation, but paradoxically colocalize in the bud… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 105 references

Self organization is the initial event in periodic feather patterning: Roles of signaling molecules and adhesion molecules

  • JIANG, T.-X, +4 authors C.-M
  • Development .
  • 1999
Highly Influential
11 Excerpts

Periodic pattern formation of the feathers

  • JUNG, H.-S, CHUONG, C.-M
  • Molecular basis of epithelial appendage…
  • 1998
Highly Influential
20 Excerpts

Early events during the regeneration of skin appendages: order of molecular reappearance following epithelial-mesenchymal recombination with rotation

  • CHUONG, C.-M, S. TING-BERRETH, R. B. WIDELITZ, JIANG, T.-X
  • J . Invest . Dermatol .
  • 1996
Highly Influential
4 Excerpts

Feather pattern formation

  • A. NOVEEN, JIANG.T.-X, CHUONG C.-M
  • 1995
Highly Influential
5 Excerpts

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