Integrons: Novel DNA elements which capture genes by site-specific recombination

@article{Hall1993IntegronsND,
  title={Integrons: Novel DNA elements which capture genes by site-specific recombination},
  author={Ruth M Hall and H. W. Stokes},
  journal={Genetica},
  year={1993},
  volume={90},
  pages={115-132}
}
Integrons are unusual DNA elements which include a gene encoding a site-specific DNA recombinase, a DNA integrase, and an adjacent site at which a wide variety of antibiotic resistance and other genes are found as inserts. One or more genes can be found in the insert region, but each gene is part of an independent gene cassette. The inserted genes are expressed from a promoter in the conserved sequences located 5′ to the genes, and integrons are thus natural expression vectors. A model for gene… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 66 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Nucleotide sequence of the AAD(2') aminoglycoside adenylyltransferase determinant aadB. Evolutionary relationship of this region with those surrounding aadA in R538-1 and dhfrll in R388

  • Cameron, EH, D. J. Groot Obbink, V. E Ackerman, R. M. Hall
  • Nucleic Acids Res
  • 1986
Highly Influential
10 Excerpts

The integron Inl in plasmid R46 includes two copies of the oxa2 gene cassette

  • H. W. Stokes
  • R.M. Hall,
  • 1992

Similar Papers

Loading similar papers…