Integrons: Novel DNA elements which capture genes by site-specific recombination

  title={Integrons: Novel DNA elements which capture genes by site-specific recombination},
  author={Ruth M Hall and H. W. Stokes},
Integrons are unusual DNA elements which include a gene encoding a site-specific DNA recombinase, a DNA integrase, and an adjacent site at which a wide variety of antibiotic resistance and other genes are found as inserts. One or more genes can be found in the insert region, but each gene is part of an independent gene cassette. The inserted genes are expressed from a promoter in the conserved sequences located 5′ to the genes, and integrons are thus natural expression vectors. A model for gene… CONTINUE READING


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