Integrity of the Pericentriolar Material Is Essential for Maintaining Centriole Association during M Phase


A procentriole is assembled next to the mother centriole during S phase and remains associated until M phase. After functioning as a spindle pole during mitosis, the mother centriole and procentriole are separated at the end of mitosis. A close association of the centriole pair is regarded as an intrinsic block to the centriole reduplication. Therefore… (More)
DOI: 10.1371/journal.pone.0138905