Integrity of membrane lipid rafts is necessary for the ordered assembly and release of infectious Newcastle disease virus particles.

@article{Laliberte2006IntegrityOM,
  title={Integrity of membrane lipid rafts is necessary for the ordered assembly and release of infectious Newcastle disease virus particles.},
  author={Jason P. Laliberte and Lori W. McGinnes and Mark E Peeples and Trudy G. Morrison},
  journal={Journal of virology},
  year={2006},
  volume={80 21},
  pages={10652-62}
}
Membrane lipid raft domains are thought to be sites of assembly for many enveloped viruses. The roles of both classical lipid rafts and lipid rafts associated with the membrane cytoskeleton in the assembly of Newcastle disease virus (NDV) were investigated. The lipid raft-associated proteins caveolin-1, flotillin-2, and actin were incorporated into virions, while the non-lipid raft-associated transferrin receptor was excluded. Kinetic analyses of the distribution of viral proteins in lipid… CONTINUE READING
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