Integrity and full coding sequence of B19 virus DNA persisting in human synovial tissue.

@article{Hokynar2000IntegrityAF,
  title={Integrity and full coding sequence of B19 virus DNA persisting in human synovial tissue.},
  author={Kati Hokynar and John D. Brunstein and Maria S{\"o}derlund-Venermo and Olli Kiviluoto and Esa K. Partio and Yrj{\"o} T. Konttinen and Klaus Hedman},
  journal={The Journal of general virology},
  year={2000},
  volume={81 Pt 4},
  pages={
          1017-25
        }
}
Primary infection by human parvovirus B19 is often accompanied by arthropathy of varying duration, of which the most severe cases can be indistinguishable from rheumatoid arthritis (RA). While this might seem to imply a role in RA pathogenesis, recent studies have verified long-term persistence of B19 DNA in synovial tissue not only in patients with rheumatoid or juvenile arthritis, but also in immunocompetent, non-arthritic individuals with a history of prior B19 infection. However, the latter… CONTINUE READING

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