Integrins in angiogenesis: multitalented molecules in a balancing act

  title={Integrins in angiogenesis: multitalented molecules in a balancing act},
  author={Kairbaan M Hodivala-Dilke and Andrew R. Reynolds and Louise E Reynolds},
  journal={Cell and Tissue Research},
Over the last 10–15 years the varied roles of cell adhesion molecules in the development of new blood vessels have received extensive attention. To date, more than 500 publications have been dedicated specifically to the role of a single family of adhesion molecules, namely integrins, in the process of angiogenesis. Although one can now appreciate the involvement of integrins in this process, and indeed antagonists of integrins are presently being tested as anti-angiogenic treatments, the… CONTINUE READING

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  • SE Francis, KL Goh, +4 authors RO Hynes
  • 2002
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