Integrins and osteoclast polarization

Abstract

The osteoclast is the principal, if not exclusive, resorptive cell of the skeleton. It is of hematopoietic origin [1] and a polykaryon with the capacity to degrade both the organic and inorganic matrices of bone [2]. The discovery that the osteoclast is a member of the monocyte/macrophage family has prompted development of models whereby this cell can be… (More)
DOI: 10.1007/BF03194343

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