Integrin receptors on aortic smooth muscle cells mediate adhesion to fibronectin, laminin, and collagen.

@article{Clyman1990IntegrinRO,
  title={Integrin receptors on aortic smooth muscle cells mediate adhesion to fibronectin, laminin, and collagen.},
  author={Ronald I. Clyman and Kevin A. McDonald and Randall H. Kramer},
  journal={Circulation research},
  year={1990},
  volume={67 1},
  pages={175-86}
}
Extracellular matrix receptors on vascular smooth muscle cells help in anchoring the cells during contraction and in promoting cellular migration after vessel injury. We found that rat aortic smooth muscle cells attach to surfaces coated with fibronectin, laminin, and collagen types I and IV. Cell attachment to these substrates appears to be mediated by members of the beta 1 integrin family of extracellular matrix receptors. Antibodies to the beta 1 subunit not only demonstrated the presence of… CONTINUE READING

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Identification and characterization of the Tlymphocyte adhesion receptor for an alternative cell attachment domain ( CS - 1 ) in plasma fibronectin

  • EA Wayner, A GariaPardo, MJ Humphries, JA McDonald, WG Carter
  • J Cell Biol
  • 1989

Characterization of the human laminin receptor ( abstract )

  • L Dillner
  • J Cell Biol
  • 1988

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