Integrin receptors and ligand-gated channels.

@article{Morini2010IntegrinRA,
  title={Integrin receptors and ligand-gated channels.},
  author={Raffaella Morini and Andrea Becchetti},
  journal={Advances in experimental medicine and biology},
  year={2010},
  volume={674},
  pages={
          95-105
        }
}
Plastic expression of different integrin subunits controls the different stages of neural development, whereas in the adult integrins regulate synaptic stability. Evidence of integrin-channel crosstalk exists for ionotropic glutamate receptors. As is often the case in other tissues, integrin engagement regulates channel activity through complex signaling pathways that often include tyrosine phosphorylation cascades. The specific pathways recruited by integrin activation depend on cerebral… CONTINUE READING
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