Integrin-linked kinase regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle.

@article{Zhang2007IntegrinlinkedKR,
  title={Integrin-linked kinase regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle.},
  author={Wenwu Zhang and Yidi Wu and Chuanyue Wu and Susan J Gunst},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 47},
  pages={34568-80}
}
The contractile stimulation of smooth muscle tissues stimulates the recruitment of proteins to membrane adhesion complexes and the initiation of actin polymerization. We hypothesized that integrin-linked kinase (ILK), a beta-integrin-binding scaffolding protein and serine/threonine kinase, and its binding proteins, PINCH, and alpha-parvin may be recruited… CONTINUE READING