Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization

Abstract

Integrin-linked kinase (ILK) is a serine-threonine kinase and scaffold protein with well defined roles in focal adhesions in integrin-mediated cell adhesion, spreading, migration, and signaling. Using mass spectrometry-based proteomic approaches, we identify centrosomal and mitotic spindle proteins as interactors of ILK. alpha- and beta-tubulin, ch-TOG… (More)
DOI: 10.1083/jcb.200710074

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