Integrin alpha6 maintains the structural integrity of the kidney collecting system.

@article{Viquez2017IntegrinAM,
  title={Integrin alpha6 maintains the structural integrity of the kidney collecting system.},
  author={Olga M Viquez and Eugenia M. Yazlovitskaya and Tianxiang Tu and Glenda Mernaugh and Pablo Secades and Karen Kulju McKee and Elizabeth Georges-Labouesse and Ad{\`e}le De Arcangelis and Vito Quaranta and Peter D Yurchenco and Leslie C Gewin and Arnoud Sonnenberg and Ambra Pozzi and Roy Zent},
  journal={Matrix biology : journal of the International Society for Matrix Biology},
  year={2017},
  volume={57-58},
  pages={244-257}
}
Laminins are a major constituent of the basement membranes of the kidney collecting system. Integrins, transmembrane receptors formed by non-covalently bound α and β subunits, serve as laminin receptors, but their role in development and homeostasis of the kidney collecting system is poorly defined. Integrin α3β1, one of the major laminin receptors, plays a minor role in kidney collecting system development, while the role of α6 containing integrins (α6β1 and α6β4), the other major laminin… CONTINUE READING
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