Integrin alpha 6 regulates glioblastoma stem cells.

  title={Integrin alpha 6 regulates glioblastoma stem cells.},
  author={J. Lathia and J. Gallagher and J. Heddleston and J. Wang and C. Eyler and J. Macswords and Q. Wu and A. Vasanji and R. McLendon and A. Hjelmeland and J. Rich},
  journal={Cell stem cell},
  volume={6 5},
  • J. Lathia, J. Gallagher, +8 authors J. Rich
  • Published 2010
  • Biology, Medicine
  • Cell stem cell
  • Cancer stem cells (CSCs) are a subpopulation of tumor cells suggested to be critical for tumor maintenance, metastasis, and therapeutic resistance. Prospective identification and targeting of CSCs are therefore priorities for the development of novel therapeutic paradigms. Although CSC enrichment has been achieved with cell surface proteins including CD133 (Prominin-1), the roles of current CSC markers in tumor maintenance remain unclear. We examined the glioblastoma stem cell (GSC… CONTINUE READING
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