Integrin activation.

  title={Integrin activation.},
  author={Darren G. Woodside and Shengquan Liu and M H Ginsberg},
  journal={Thrombosis and haemostasis},
  volume={86 1},
Integrins are cell surface adhesion receptors that participate in a variety of important processes throughout the vasculature. Here we summarize some recent findings on the regulation of integrin mediated cellular adhesion. Particular emphasis is placed on the regulation of integrin affinity for ligand (activation), although this is just one mechanism by which regulation of integrin-dependent cell adhesion can occur. Also discussed are recent observations on the structural basis of integrin… CONTINUE READING

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