Integrin Signalling and the Cellular Response to Ionizing Radiation

  title={Integrin Signalling and the Cellular Response to Ionizing Radiation},
  author={Nils Cordes and Viktor Meineke},
  journal={Journal of Molecular Histology},
Cell survival and cycling in mammalian cells are both greatly affected by ionizing radiation and are both strictly controlled by integrated integrin-mediated adhesion to extracellular matrix (ECM) proteins and by binding of growth factors to their cognate receptors. Recent emerging findings show a diverse panel of integrin-dependent signals that are channelled into the regulation and modification of the cellular response to ionizing radiation. Cell adhesion-mediated radioresistance and… CONTINUE READING

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