Integrin-Linked Kinase Controls Microtubule Dynamics Required for Plasma Membrane Targeting of Caveolae

@inproceedings{Wickstrm2010IntegrinLinkedKC,
  title={Integrin-Linked Kinase Controls Microtubule Dynamics Required for Plasma Membrane Targeting of Caveolae},
  author={Sara A Wickstr{\"o}m and Anika Lange and Michael W Hess and Julien Polleux and Joachim P Spatz and Marcus Krueger and Kristian Pfaller and Armin Lambacher and Wilhelm Bloch and Matthias Mann and Lukas A. Huber and Reinhard F{\"a}ssler},
  booktitle={Developmental cell},
  year={2010}
}
Caveolae are specialized compartments of the plasma membrane that are involved in signaling, endocytosis, and cholesterol transport. Their formation requires the transport of caveolin-1 to the plasma membrane, but the molecular mechanisms regulating the transport are largely unknown. Here, we identify a critical role for adhesion-mediated signaling through β1 integrins and integrin-linked kinase (ILK) in caveolae formation. Mice lacking β1 integrins or ILK in keratinocytes have dramatically… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 87 CITATIONS, ESTIMATED 63% COVERAGE

Integrins and epithelial cell polarity.

  • Journal of cell science
  • 2014
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Microtubules in cell migration.

  • Annual review of cell and developmental biology
  • 2013
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Integrin-linked kinase regulates cellular mechanics facilitating the motility in 3D extracellular matrices.

  • Biochimica et biophysica acta. Molecular cell research
  • 2017
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling.

  • Current opinion in cell biology
  • 2012
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2011
2019

CITATION STATISTICS

  • 8 Highly Influenced Citations

  • Averaged 5 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 57 REFERENCES

Assembly and trafficking of caveolar domains in the cell

  • The Journal of cell biology
  • 2005
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL