Integrative network analysis reveals active microRNAs and their functions in gastric cancer

@inproceedings{Tseng2011IntegrativeNA,
  title={Integrative network analysis reveals active microRNAs and their functions in gastric cancer},
  author={Chien-Wei Tseng and Chen-Ching Lin and Chiung-Nien Chen and Hsuan-Cheng Huang and Hsueh-Fen Juan},
  booktitle={BMC Systems Biology},
  year={2011}
}
MicroRNAs (miRNAs) are a class of endogenous, small and highly conserved noncoding RNAs that control gene expression either by degradation of target mRNAs or by inhibition of protein translation. They play important roles in cancer progression. A single miRNA can provoke a chain reaction and further affect protein interaction network (PIN). Therefore, we developed a novel integrative approach to identify the functional roles and the regulated PIN of oncomirs. We integrated the expression… CONTINUE READING
Highly Cited
This paper has 76 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 52 extracted citations

77 Citations

051015'13'15'17'19
Citations per Year
Semantic Scholar estimates that this publication has 77 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Human Protein Reference Database—2009 update

Nucleic Acids Research • 2006
View 3 Excerpts
Highly Influenced

Significance analysis of microarrays applied to the ionizing radiation response.

Proceedings of the National Academy of Sciences of the United States of America • 2001
View 2 Excerpts
Highly Influenced

Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer.

Proceedings of the National Academy of Sciences of the United States of America • 2011
View 1 Excerpt

Let-7 microRNA inhibits the proliferation of human glioblastoma cells

Journal of Neuro-Oncology • 2010
View 1 Excerpt