Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines.

  • Hao Wu, Jun Xu, +6 authors Yi Sun
  • Published 2007 in
    Proceedings of the National Academy of Sciences…


The self-renewal and differentiation potential of human embryonic stem cells (hESCs) suggests that hESCs could be used for regenerative medicine, especially for restoring neuronal functions in brain diseases. However, the functional properties of neurons derived from hESC are largely unknown. Moreover, because hESCs were derived under diverse conditions… (More)

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