Integrative genomic analyses of WNT 11 : Transcriptional mechanisms based on canonical WNT signals and GATA transcription factors

    Abstract

    We and others previously cloned and characterized vertebrate WNT11 orthologs, which are involved in gastrulation, neurulation, cardiogenesis, nephrogenesis, and chondrogenesis during fetal development. WNT11 orthologs activate both canonical and non-canonical WNT signaling cascades depending on the expression profile of WNT receptors, such as Frizzled… (More)

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