Integrative circuit models and their implications for the pathophysiologies and treatments of the schizophrenias.

@article{Swerdlow2010IntegrativeCM,
  title={Integrative circuit models and their implications for the pathophysiologies and treatments of the schizophrenias.},
  author={Neal R. Swerdlow},
  journal={Current topics in behavioral neurosciences},
  year={2010},
  volume={4},
  pages={555-83}
}
A preponderance of evidence indicates that the heterogeneous group of schizophrenias is accompanied by disturbances in neural elements distributed throughout multiple levels of interconnected cortico-striato-pallido-thalamic circuitry. These disturbances include a substantial loss of, or failure to develop, both cells and/or appropriate cellular connections in regions that include at least portions of the hippocampus, parahippocampal gyrus, entorhinal cortex, amygdala, prefrontal and anterior… CONTINUE READING

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