Integrative biological simulation praxis: Considerations from physics, philosophy, and data/model curation practices

@article{Sarma2017IntegrativeBS,
  title={Integrative biological simulation praxis: Considerations from physics, philosophy, and data/model curation practices},
  author={Gopal P. Sarma and V{\'i}ctor E. Olivares Fa{\'u}ndez},
  journal={Cellular Logistics},
  year={2017},
  volume={7}
}
ABSTRACT Integrative biological simulations have a varied and controversial history in the biological sciences. From computational models of organelles, cells, and simple organisms, to physiological models of tissues, organ systems, and ecosystems, a diverse array of biological systems have been the target of large-scale computational modeling efforts. Nonetheless, these research agendas have yet to prove decisively their value among the broader community of theoretical and experimental… 
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