Integrative Structure Modeling of Macromolecular Assemblies from Proteomics Data*

  title={Integrative Structure Modeling of Macromolecular Assemblies from Proteomics Data*},
  author={Keren Lasker and Jeremy Phillips and Daniel Russel and Javier A. Vel{\'a}zquez-Muriel and Dina Schneidman-Duhovny and Elina Tjioe and Ben M. Webb and Avner Schlessinger and Andrej Sali},
  journal={Molecular \& Cellular Proteomics},
  pages={1689 - 1702}
Proteomics techniques have been used to generate comprehensive lists of protein interactions in a number of species. However, relatively little is known about how these interactions result in functional multiprotein complexes. This gap can be bridged by combining data from proteomics experiments with data from established structure determination techniques. Correspondingly, integrative computational methods are being developed to provide descriptions of protein complexes at varying levels of… 

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