Integrative Genomic and Transcriptomic Characterization of Matched Primary and Metastatic Liver and Colorectal Carcinoma

@inproceedings{Roessler2015IntegrativeGA,
  title={Integrative Genomic and Transcriptomic Characterization of Matched Primary and Metastatic Liver and Colorectal Carcinoma},
  author={Stephanie Roessler and Guoling Lin and Marshonna Forgues and Anuradha S. Budhu and Shelley B. Hoover and Robert Mark Simpson and Xiaolin Wu and Ping He and Lunxiu Qin and Zhao-you Tang and Qing-hai Ye and Xin Wei Wang},
  booktitle={International journal of biological sciences},
  year={2015}
}
Metastasis is the main cause of cancer mortality but its process remains poorly understood and thus hampers more effective treatment and improved cancer prognosis. To search for metastasis driver genes responsible for tumor spread, we integrated genomic and transcriptomic profiles of 61 matched primary tumors and distant metastases of liver or colorectal carcinoma isolated by laser-capture microdissection and assayed by array-based technologies. We found that primary tumor lesions and their… CONTINUE READING
Highly Cited
This paper has 19 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Similar Papers

Loading similar papers…