Integration of the cytogenetic map with the draft human genome sequence.

@article{Furey2003IntegrationOT,
  title={Integration of the cytogenetic map with the draft human genome sequence.},
  author={Terrence S. Furey and David Haussler},
  journal={Human molecular genetics},
  year={2003},
  volume={12 9},
  pages={
          1037-44
        }
}
Chemically staining metaphase chromosomes resulting in an alternating dark and light banding pattern provide a tool by which abnormalities in chromosomes from diseased cells can be identified. The localization of these aberrations to a chromosomal region provides clues as to which gene or genes may contribute to a particular disease. With the sequencing of the human genome, it became critical to determine the positions of these cytogenetic bands within the sequence in order to take advantage of… CONTINUE READING

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