Integration of phytochemicals and phytotherapy into cancer precision medicine

  title={Integration of phytochemicals and phytotherapy into cancer precision medicine},
  author={Thomas H Efferth and Mohamed E. M. Saeed and Elhaj Mirghani and Awadh Alim and Zahir Yassin and Elfatih M Saeed and Hassan El-Subiki Khalid and Salah Daak},
Concepts of individualized therapy in the 1970s and 1980s attempted to develop predictive in vitro tests for individual drug responsiveness without reaching clinical routine. Precision medicine attempts to device novel individual cancer therapy strategies. Using bioinformatics, relevant knowledge is extracted from huge data amounts. However, tumor heterogeneity challenges chemotherapy due to genetically and phenotypically different cell subpopulations, which may lead to refractory tumors… CONTINUE READING
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