Integration of human sleep-wake regulation and circadian rhythmicity.

@article{Dijk2002IntegrationOH,
  title={Integration of human sleep-wake regulation and circadian rhythmicity.},
  author={D. Dijk and S. Lockley},
  journal={Journal of applied physiology},
  year={2002},
  volume={92 2},
  pages={
          852-62
        }
}
The human sleep-wake cycle is generated by a circadian process, originating from the suprachiasmatic nuclei, in interaction with a separate oscillatory process: the sleep homeostat. The sleep-wake cycle is normally timed to occur at a specific phase relative to the external cycle of light-dark exposure. It is also timed at a specific phase relative to internal circadian rhythms, such as the pineal melatonin rhythm, the circadian sleep-wake propensity rhythm, and the rhythm of responsiveness of… Expand
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