Integration of cell phone imaging with microchip ELISA to detect ovarian cancer HE4 biomarker in urine at the point-of-care.

@article{Wang2011IntegrationOC,
  title={Integration of cell phone imaging with microchip ELISA to detect ovarian cancer HE4 biomarker in urine at the point-of-care.},
  author={Shuqi Wang and Xiaohu Zhao and Imran Khimji and Ragip Akbas and Weiliang Qiu and Dale Edwards and Daniel W Cramer and B. Ye and Utkan Demirci},
  journal={Lab on a chip},
  year={2011},
  volume={11 20},
  pages={3411-8}
}
Ovarian cancer is asymptomatic in the early stages and most patients present with advanced levels of disease. The lack of cost-effective methods that can achieve frequent, simple and non-invasive testing hinders early detection and causes high mortality in ovarian cancer patients. Here, we report a simple and inexpensive microchip ELISA-based detection module that employs a portable detection system, i.e., a cell phone/charge-coupled device (CCD) to quantify an ovarian cancer biomarker, HE4, in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 56 extracted citations

References

Publications referenced by this paper.
Showing 1-7 of 7 references

Kidney Int. 2010; 78:486–494

  • SS Waikar, VS Sabbisetti, JV. Bonventre
  • Author manuscript; available in PMC 2013…
  • 2013

Page 8 Lab Chip

  • S Wang, F Xu, Adv. Demirci U. Biotechnol
  • Author manuscript; available in PMC 2013…
  • 2013

Biosensors & Bioelectronics

  • KY Lien, LY Hung, TB Huang, YC Tsai, HY Lei, GB. Lee
  • 2011

Current Opinion in Obstetrics & Gynecology

  • A Gagnon, B. Ye
  • 2008

Gynecologic Oncology

  • JR van Nagell, PD Depriest, +4 authors RJ. Kryscio
  • 2000

Similar Papers

Loading similar papers…