Integration of Silicon and Printed Electronics for Rapid Diagnostic Disease Biosensing

@article{Thomas2016IntegrationOS,
  title={Integration of Silicon and Printed Electronics for Rapid Diagnostic Disease Biosensing},
  author={Daniel J. Thomas and Zari Tehrani},
  journal={Point of Care: The Journal of Near-patient Testing \& Technology},
  year={2016},
  volume={15},
  pages={61-71}
}
AbstractDuring this research, we developed a printed point-of-care device that was integrated with a biosensing silicon sensor. This resulted in the detection of a specific biomarker, which indicates the presence of a series of common diseases. The selective detection of biomarkers is an important c 

References

SHOWING 1-10 OF 30 REFERENCES
3D integration technology for lab-on-a-chip applications
A review is presented of advances and challenges in fully integrated systems for personalised medicine applications. One key issue for the commercialisation of such systems is the disposability of
Silicon Nanowire Immunosensor for Detection of 8-Hydroxy-2'-Deoxyguanosine Oxidative Stress Cancer Biomarker
TLDR
The antibody-functionalised SiNW sensor has been used to detect binding of the 8-OHdG biomarker to the SiNW surface within sixty-seconds of exposure, making this a rapid cancer biomarker test.
Top-down fabricated silicon nanowire sensors for real-time chemical detection.
TLDR
Silicon nanowire sensors developed by using top-down fabrication that is CMOS (complementary metal-oxide-semiconductor) compatible for resistive chemical detection with fast response and high sensitivity for pH detection and the long term drifting effects were investigated.
Sequence-Specific Label-Free DNA Sensors Based on Silicon Nanowires
TLDR
Highly sensitive and sequence-specific DNA sensors were fabricated based on silicon nanowires with single stranded probe DNA molecules covalently immobilized on the nanowire surfaces, recognizing label-free complementary ss-DNA in sample solutions when the target DNA was hybridized with the probe DNA attached on the SiNW surfaces.
Low cost and manufacturable complete microTAS for detecting bacteria.
TLDR
A fully integrated lab-on-a-chip and associated instrument for the detection of bacteria from liquid samples and a prototype instrument to automate control of the fluids, temperature cycling, and optical detection with the capability of accommodating various chip designs is built.
The Use of Impedance Spectroscopy for the Characterization of Protein-Modified ISFET Devices: Application of the Method for the Analysis of Biorecognition Processes
Impedance spectroscopy is used to characterize the structure of biomaterial layers on the gate surface of ISFET devices, and to elucidate antigen−antibody binding interactions on the gate interface.
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