Integration and saturation within the circadian photic entrainment pathway of hamsters.

@article{Nelson1999IntegrationAS,
  title={Integration and saturation within the circadian photic entrainment pathway of hamsters.},
  author={Dwight E. Nelson and Joseph S Takahashi},
  journal={The American journal of physiology},
  year={1999},
  volume={277 5 Pt 2},
  pages={R1351-61}
}
The sensitivity of the visual pathway that subserves circadian entrainment was measured in hamsters after prior stimulation and using trains of multiple pulses. Immediately after subsaturating stimulation in the late subjective night, there was a significant decrease in responsiveness that persisted for at least 1 h. The reduced responsiveness was not due to light adaptation (shifting of the stimulus-response curve) but rather to response saturation, which appeared to reduce the sensitivity to… CONTINUE READING