Integration and organization of Ti plasmid sequences in crown gall tumors.

@article{Thomashow1980IntegrationAO,
  title={Integration and organization of Ti plasmid sequences in crown gall tumors.},
  author={Michael F Thomashow and Robert D. Nutter and Alice L. Montoya and Milton Paul Gordon and Eugene W. Nester},
  journal={Cell},
  year={1980},
  volume={19 3},
  pages={729-39}
}
The Ti plasmid sequences (T DNA) maintained in four unorganized crown gall tumor lines were defined by using restriction endonucleases and molecular hybridization techniques. Each tumor line contains a "core" T DNA which is apparently responsible for maintaining the transformed state; the core T DNA is colinear with the Ti plasmid and contains the Ti plasmid sequences referred to as the "common DNA"--sequences found in all Ti plasmids studied to date. A given Ti plasmid does not always give… CONTINUE READING
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