Integrating systems biology sources illuminates drug action

@inproceedings{Gottlieb2014IntegratingSB,
  title={Integrating systems biology sources illuminates drug action},
  author={Assaf Gottlieb and Russ B. Altman},
  booktitle={Clinical pharmacology and therapeutics},
  year={2014}
}
There are significant gaps in our understanding of the pathways by which drugs act. This incomplete knowledge limits our ability to use mechanistic molecular information rationally to repurpose drugs, understand their side effects, and predict their interactions with other drugs. Here, we present DrugRouter, a novel method for generating drug-specific… CONTINUE READING