Integrating maps of chromosome 16.

  title={Integrating maps of chromosome 16.},
  author={John C. Mulley and Grant R. Sutherland},
  journal={Current opinion in genetics & development},
  volume={3 3},
The recently published, detailed cytogenetic-based physical map of chromosome 16 has the highest resolution of any autosomal cytogenetic map thus far constructed. The genetic map has been integrated with the cytogenetic map to facilitate the regional localization of disease genes by linkage. Disease genes for tuberous sclerosis, familial Mediterranean fever, Rubinstein-Taybi syndrome and Morquio A syndrome have now been assigned to chromosome 16. The search for the adult polycystic kidney… CONTINUE READING