Integrating human and rodent data to identify the genetic factors involved in chronic kidney disease.

@article{Garrett2010IntegratingHA,
  title={Integrating human and rodent data to identify the genetic factors involved in chronic kidney disease.},
  author={Michael R. Garrett and Marcus G Pezzolesi and Ron Korstanje},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2010},
  volume={21 3},
  pages={
          398-405
        }
}
The increasing numbers of patients with chronic kidney disease combined with no satisfying interventions for preventing or curing the disease emphasize the need to better understand the genes involved in the initiation and progression of complex renal diseases, their interactions with other host genes, and the environment. Linkage and association studies in human, rat, and mouse have been successful in identifying genetic loci for various disease-related phenotypes but have thus far not been… CONTINUE READING

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