Integrating health status and survival data: the palliative effect of lung volume reduction surgery.

@article{Benzo2009IntegratingHS,
  title={Integrating health status and survival data: the palliative effect of lung volume reduction surgery.},
  author={Roberto P Benzo and Max H. Farrell and Chung-Chou Ho Chang and Fernando J Martinez and Robert M. Kaplan and John C Reilly and Gerard J. Criner and Robert S Wise and Barry J. Make and James T. Luketich and Alfred P. Fishman and Frank C. Sciurba},
  journal={American journal of respiratory and critical care medicine},
  year={2009},
  volume={180 3},
  pages={239-46}
}
RATIONALE In studies that address health-related quality of life (QoL) and survival, subjects who die are usually censored from QoL assessments. This practice tends to inflate the apparent benefits of interventions with a high risk of mortality. Assessing a composite QoL-death outcome is a potential solution to this problem. OBJECTIVES To determine the effect of lung volume reduction surgery (LVRS) on a composite endpoint consisting of the occurrence of death or a clinically meaningful… CONTINUE READING

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