Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes.

@article{Lieber1999IntegratingAV,
  title={Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes.},
  author={Andr{\'e} Lieber and Dirk S. Steinwaerder and Cheryl A. Carlson and Mark A. Kay},
  journal={Journal of virology},
  year={1999},
  volume={73 11},
  pages={9314-24}
}
Recently, we demonstrated that inverted repeat sequences inserted into first-generation adenovirus (Ad) vector genomes mediate precise genomic rearrangements resulting in vector genomes devoid of all viral genes that are efficiently packaged into functional Ad capsids. As a specific application of this finding, we generated adenovirus-adeno-associated virus (AAV) hybrid vectors, first-generation Ad vectors containing AAV inverted terminal repeat sequences (ITRs) flanking a reporter gene… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Adenovirus-mediated delivery of an EBV-based replicon via Cre/loxP recombination: a novel vector system for efficient and long-term gene expression, abstr

  • H. Leblois, C. Orsini, P. Yeh, M. Perricaudet
  • p. 177a. Presented at the 1st meeting of the…
  • 1998

Similar Papers

Loading similar papers…