Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens

@inproceedings{Chasman2016IntegratingTA,
  title={Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens},
  author={Deborah Chasman and Kevin B. Walters and Tiago J. S. Lopes and Amie J. Eisfeld and Yoshihiro Kawaoka and Sushmita Roy},
  booktitle={PLoS Computational Biology},
  year={2016}
}
Mammalian host response to pathogenic infections is controlled by a complex regulatory network connecting regulatory proteins such as transcription factors and signaling proteins to target genes. An important challenge in infectious disease research is to understand molecular similarities and differences in mammalian host response to diverse sets of pathogens. Recently, systems biology studies have produced rich collections of omic profiles measuring host response to infectious agents such as… CONTINUE READING
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