Integrating Transcriptome and Epigenome: Putting Together the Pieces of the Type 2 Diabetes Pathogenesis Puzzle

Abstract

The complex pathophysiological process of type 2 diabetes (T2D) involves perturbation of gene expression, leading to derangement of multiple physiological processes in tissues that are important in glucose homeostasis (1). Interactions of environmental factors with genetic and epigenetic variants are likely to play an important role; however, the relative… (More)
DOI: 10.2337/db14-0757

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