Integrated wall stress: a new methodological approach to assess ventricular workload and myocardial contractile reserve

@inproceedings{Dong2013IntegratedWS,
  title={Integrated wall stress: a new methodological approach to assess ventricular workload and myocardial contractile reserve},
  author={Hailong L. Dong and Heather Mosca and Erzhuo Gao and Robert E. Akins and Samuel S. Gidding and Takeshi Tsuda},
  booktitle={Journal of Translational Medicine},
  year={2013}
}
Wall stress is a useful concept to understand the progression of ventricular remodeling. We measured cumulative LV wall stress throughout the cardiac cycle over unit time and tested whether this “integrated wall stress (IWS)” would provide a reliable marker of total ventricular workload. We applied IWS to mice after experimental myocardial infarction (MI) and sham-operated mice, both at rest and under dobutamine stimulation. Small infarcts were created so as not to cause subsequent overt… CONTINUE READING
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