Integrated view on 17beta-hydroxysteroid dehydrogenases

  title={Integrated view on 17beta-hydroxysteroid dehydrogenases},
  author={G. Moeller and J. Adamski},
  journal={Molecular and Cellular Endocrinology},
  • G. Moeller, J. Adamski
  • Published 2009
  • Biology, Medicine
  • Molecular and Cellular Endocrinology
  • 17beta-Hydroxysteroid dehydrogenases (17beta-HSDs) are important enzymes in steroid metabolism. Long known members of the protein family seemed to be well characterised concerning their role in the regulation of the biological potency of steroid hormones, but today more and more evidence points to pivotal contributions of these enzymes in a variety of other metabolic pathways. Therefore, studies on 17beta-HSDs develop towards metabolomic survey. Latest research results give new insights into… CONTINUE READING
    177 Citations
    Recent advances in 17beta-hydroxysteroid dehydrogenases
    • 50
    Multifunctionality in the enzyme family of 17beta-hydroxysteroid dehydrogenases
    • PDF
    Substrate multispecificity among 20β-hydroxysteroid dehydrogenase type 2 members
    17β-Hydroxysteroid dehydrogenase inhibitors: a patent review
    • D. Poirier
    • Biology, Medicine
    • Expert opinion on therapeutic patents
    • 2010
    • 70
    17B-hydroxysteroid dehydrogenases as acyl thioester metabolizing enzymes
    • 3
    Subcellular localization and membrane topology of 17β-hydroxysteroid dehydrogenases
    • 5


    Multifunctionality of human 17beta-hydroxysteroid dehydrogenases.
    • 30
    Multifunctionality of human 17β-hydroxysteroid dehydrogenases
    • 111
    Structure and function of human 17β-hydroxysteroid dehydrogenases
    • 124
    17β-hydroxysteroid dehydrogenase type 7 — an ancient 3-ketosteroid reductase of cholesterogenesis
    • 52
    • PDF
    Perspectives in Understanding the Role of Human 17β‐Hydroxysteroid Dehydrogenases in Health and Disease
    • 35
    Promoter analyses of human and mouse 17beta-hydroxysteroid dehydrogenase type 7
    • 9