Integrated treatment ameliorates negative symptoms in first episode psychosis--results from the Danish OPUS trial.

@article{Thorup2005IntegratedTA,
  title={Integrated treatment ameliorates negative symptoms in first episode psychosis--results from the Danish OPUS trial.},
  author={Anne Amalie Elgaard Thorup and Lone Keld Petersen and Pia Jeppesen and Johan Ohlenschlaeger and Torben \Ostergaard Christensen and Gertrud Krarup and Per Gorm J\orgensen and Merete Nordentoft},
  journal={Schizophrenia research},
  year={2005},
  volume={79 1},
  pages={95-105}
}
PURPOSE To investigate the effect of integrated treatment on negative, psychotic and disorganised symptoms in patients with first episode psychosis. METHOD A RCT comparing integrated treatment (IT) with standard treatment (ST) was conducted, including 547 patients, aged 18-45, diagnosed with schizophrenia spectrum disorders. All patients were assessed with SCAN, SAPS and SANS at entry and after 1 and 2 years. The IT consisted of assertive community treatment, multifamily groups, psycho… CONTINUE READING

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